Jarrow Formulas SAM_e_ Promotes Joint Strength_ Mood and Brain Function_ 400 mg_ 30 Enteric_ Coated tabs

Product Description Product Profile S-adenosyl-L-methionine (SAM-e) is an amino acid derivative clinically documented to benefit brain, liver and joint function.* Found in all living cells, SAM-e is called “activated methionine” and is formed via combination of ATP with methionine. Somewhat counterintuitively, however, methionine supplementation does not elevate SAM-e levels in the body. Rather, it elevates problematic homocysteine. SAM-e has undergone many clinical trials involving thousands of human subjects. Researchers have identified many structure- and function-based benefits of SAM-e involving over 40 biochemical processes. It is a biochemical workhorse with various diverse effects on the body, including improving liver function, supporting joint health, and lifting mood.* Distinguishing Features: Predominantly active S,S form Produced naturally via fermentation Processed without solvents Protected from degradation via enteric coating & blister-packaging Preserved bioavailability through low-temp & low-moisture manufacturing Liver Detoxification And Brain Function SAM-e metabolism supports glutathione (GSH) synthesis and glutathione-dependent enzymes, which support liver function.* GSH, the chief antioxidant and detoxifier inside cells, scavenges free radicals produced during carbohydrate breakdown for energy. Taurine is another end product of SAM-e metabolism. GSH and taurine are important for liver detoxification.* SAM-e supports brain function by its methylation effects.* Methylation is the transfer of a methyl group (one carbon and three hydrogen atoms, CH3) from one molecule to another. SAM-e is the most important of all methyl-donors in mammalian metabolism. Donation of methyl groups supports numerous metabolic processes including brain function, energy production, and DNA metabolism. Neurotransmitters, substances involved in nerve cell communication, are also products of methylation. These compounds include L-DOPA, dopamine, serotonin, epinephrine, and phosphatidylcholine (in lecithin). SAM-e is thought to benefit cognitive health by supporting the production of such critical brain messengers.* In fact, many people report noticeable positive effects on brain and mood after only taking it for a short time.* Not All SAM-e Is Created Equal SAM-e exists in two forms: (S,S) SAM-e and (R,S) SAM-e. The biol