Jarrow Formulas Glucosamine and Chondroitin Supports Joint Health 240 Caps

Glucosamine + Chondroitin is Joint Sustaining Nutrition Joints and connective tissues both hold us together and keep us apart. Ligaments and tendons, and even muscle, mostly do the binding. Whereas it is joints, including cartilage and synovial fluid, that are mostly responsible for keeping bones from grinding against one another. This is a difficult task, as the amount of impact force that joints can cushion is far more effective than any man-made material. Though our joints are difficult to rebuild once they’ve deteriorated, there are some nutrients that can help maintain joint health.* What Distinguishes this Product? Sodium-Free Glucosamine Sulfate 1.5 g Glucosamine Sulfate and 1.2 g Chondroitin Sulfate Per Serving Quantities consistent with clinical research Also Contains Vitamin C and Manganese Useful in the synthesis of collagen and cartilage Glucosamine: Hyaluronic Acid Precursor Glucosamine is a building block of hyaluronic acid, and is found in high quantities in the joints. Hyaluronic acid is synthesized by hyaluronic acid synthases (HAS), which covalently link monomeric N-acetyl-glucosamine, a derivative of glucosamine, and glucuronic acid in alternating fashion. In one randomized, double-blind, placebo-controlled trial the effect of 1500 mg/day of oral glucosamine from glucosamine sulfate was examined in 202 human subjects over three years. The glucosamine group maintained joint width over the course of the trial, while the placebo group did not. Results on the two groups using the Lequesne index, the WOMAC total index, and functional subscales indicated support for joint function and mobility, as well.* Chondroitin Although usually studied independently, some reports have indicated that glucosamine sulfate (GS) and chondroitin sulfate work synergistically. Chondroitin sulfate is the perfect complement to GS since chondroitin acts like a biological version of a “liquid magnet,” attracting fluid into proteoglycans. This fluid acts as a shock absorber and also brings nutrients with it into the cartilage. Perhaps of greater significance than its fluid-enhancing properties, chondroitin protects existing cartilage through its modulatory effects on enzymes that degrade cartilage.* Furthermore, like GS, chondroitin stimulates the production of proteoglycans and collagen that are needed for the maintenance of healthy cartila